CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Longitudinal bone growth ceases with growth plate senescence during puberty. However, the molecular mechanisms of this phenomenon are largely unexplored. Here, we examined Wnt-responsive genes before and after growth plate senescence and found that CXXC finger protein 5 (CXXC5), a negative regulator...

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Vydáno v:Life Sci Alliance
Hlavní autoři: Choi, Sehee, Kim, Hyun-Yi, Cha, Pu-Hyeon, Seo, Seol Hwa, Lee, Chulho, Choi, Yejoo, Shin, Wookjin, Heo, Yunseok, Han, Gyoonhee, Lee, Weontae, Choi, Kang-Yell
Médium: Artigo
Jazyk:Inglês
Vydáno: Life Science Alliance LLC 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458850/
https://ncbi.nlm.nih.gov/pubmed/30971423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800254
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