Depletion of ATP-Citrate Lyase (ATPCL) Affects Chromosome Integrity Without Altering Histone Acetylation in Drosophila Mitotic Cells

The Citrate Lyase (ACL) is the main cytosolic enzyme that converts the citrate exported from mitochondria by the SLC25A1 carrier in Acetyl Coenzyme A (acetyl-CoA) and oxaloacetate. Acetyl-CoA is a high-energy intermediate common to a large number of metabolic processes including protein acetylation...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Morciano, Patrizia, Di Giorgio, Maria Laura, Porrazzo, Antonella, Licursi, Valerio, Negri, Rodolfo, Rong, Yikang, Cenci, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458238/
https://ncbi.nlm.nih.gov/pubmed/31019471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00383
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