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Roles of cellular heterogeneity, intrinsic and extrinsic noise in variability of p53 oscillation

The p53 protein is a key mediator of the cellular response to various stress signals. In response to DNA damage, the concentration of p53 can temporally oscillate with fluctuations in both the amplitude and period. The underlying mechanism for p53 variability is not fully understood. Here, we constr...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Wang, Dao-Guang, Wang, Shaobing, Huang, Bo, Liu, Feng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458166/
https://ncbi.nlm.nih.gov/pubmed/30971810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41904-9
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