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Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling

BACKGROUND: The p53 protein is the best studied target in human cancer. For decades, p53 has been believed to act mainly as a tumor suppressor and by transcriptional regulation. Only recently, the complex and diverse function of p53 has attracted more attention. Using several molecular approaches, w...

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Detalhes bibliográficos
Main Authors: Wachter, Franziska, Grunert, Michaela, Blaj, Cristina, Weinstock, David M, Jeremias, Irmela, Ehrhardt, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641951/
https://ncbi.nlm.nih.gov/pubmed/23594441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-27
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