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Modulating Aptamer Specificity with pH-Responsive DNA Bonds

Aptamers that recognize specific cells in a complex environment have emerged as invaluable molecular tools in bioanalysis and in the development of targeted therapeutics. The selective recognition of aptamers, however, can be compromised by the coexistence of target receptors on both target cells an...

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Dettagli Bibliografici
Pubblicato in:J Am Chem Soc
Autori principali: Li, Long, Jiang, Ying, Cui, Cheng, Yang, Yu, Zhang, Penghui, Stewart, Kimberly, Pan, Xiaoshu, Li, Xiaowei, Yang, Lu, Qiu, Liping, Tan, Weihong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457906/
https://ncbi.nlm.nih.gov/pubmed/30212189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08047
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