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Identification and Characterization of DNA Aptamers Specific for Phosphorylation Epitopes of Tau Protein
Tau proteins are proteins that stabilize micro-tubules, but their hyperphosphorylation can result in the formation of protein aggregates and, over time, neuro-degeneration. This phenomenon, termed tauopathy, is pathologically involved in several neurodegenerative disorders. DNA aptamers are single-s...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442731/ https://ncbi.nlm.nih.gov/pubmed/30277395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08645 |
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