Splitomicin, a SIRT1 Inhibitor, Enhances Hematopoietic Differentiation of Mouse Embryonic Stem Cells

BACKGROUND AND OBJECTIVES: Embryonic stem (ES) cells have pluripotent ability to differentiate into multiple tissue lineages. SIRT1 is a class III histone deacetylase which modulates chromatin remodeling, gene silencing, cell survival, metabolism, and development. In this study, we examined the effe...

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Bibliografske podrobnosti
izdano v:Int J Stem Cells
Main Authors: Park, Jeong-A, Park, Sangkyu, Park, Woo-Youn, Han, Myung-Kwan, Lee, Younghee
Format: Artigo
Jezik:Inglês
Izdano: Korean Society for Stem Cell Research 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457709/
https://ncbi.nlm.nih.gov/pubmed/30836727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc18040
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