Inhibition of MUC1-C Increases ROS and Cell Death in Mouse Embryonic Stem Cells

BACKGROUND AND OBJECTIVES: Embryonic stem (ES) cells have the capacity to self-renew and generate all types of cells. MUC1-C, a cytoplasmic subunit of MUC1, is overexpressed in various carcinomas and mediates signaling pathways to regulate intracellular metabolic processes and gene expression involv...

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Veröffentlicht in:Int J Stem Cells
Hauptverfasser: Park, Jeong-A, Park, Sangkyu, Choi, Jun-Kyu, Han, Myung-Kwan, Lee, Younghee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Stem Cell Research 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138657/
https://ncbi.nlm.nih.gov/pubmed/33122470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc20089
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