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Monodisperse polysarcosine-based highly-loaded antibody-drug conjugates
Antibody-drug conjugates (ADCs) convey highly potent anticancer drugs to antigen-expressing tumor cells, thereby sparing healthy tissues throughout the body. Pharmacokinetics and tolerability of ADCs are predominantly influenced by the drug-antibody ratio (DAR) of the conjugates, which is to-date li...
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| Udgivet i: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6457330/ https://ncbi.nlm.nih.gov/pubmed/31015945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc00285e |
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