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PHOSPHATIDYLINOSITOL AND PHOSPHATIDIC ACID TRANSPORT BETWEEN THE ER AND PLASMA MEMBRANE DURING PLC ACTIVATION REQUIRES THE NIR-2 PROTEIN
Phospholipase C (PLC)-mediated hydrolysis of the limited pool of plasma membrane (PM) phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P(2)] requires replenishment from a larger pool of phosphatidylinositol (PtdIns) via sequential phosphorylation by PI 4-kinases and PIP 5-kinases. Since PtdIns is s...
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| Udgivet i: | Biochem Soc Trans |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6456894/ https://ncbi.nlm.nih.gov/pubmed/26862206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20150187 |
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