PHOSPHATIDYLINOSITOL AND PHOSPHATIDIC ACID TRANSPORT BETWEEN THE ER AND PLASMA MEMBRANE DURING PLC ACTIVATION REQUIRES THE NIR-2 PROTEIN

Phospholipase C (PLC)-mediated hydrolysis of the limited pool of plasma membrane (PM) phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P(2)] requires replenishment from a larger pool of phosphatidylinositol (PtdIns) via sequential phosphorylation by PI 4-kinases and PIP 5-kinases. Since PtdIns is s...

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Publicado en:Biochem Soc Trans
Main Authors: Kim, Yeun Ju, Hernandez, Maria Luisa Guzman, Wisniewski, Eva, Echeverria, Nicolas, Balla, Tamas
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456894/
https://ncbi.nlm.nih.gov/pubmed/26862206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20150187
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