Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics

Brown and beige adipocytes are enriched in mitochondria with uncoupling protein-1 (UCP1) to generate heat instead of ATP contributing to healthy energy balance. There are few human cellular models to reveal regulatory networks in adipocyte browning and key targets for enhancing thermogenesis in obes...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Klusóczki, Ágnes, Veréb, Zoltán, Vámos, Attila, Fischer-Posovszky, Pamela, Wabitsch, Martin, Bacso, Zsolt, Fésüs, László, Kristóf, Endre
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456729/
https://ncbi.nlm.nih.gov/pubmed/30967578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42256-0
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