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THP-1 Macrophages and SGBS Adipocytes – A New Human in vitro Model System of Inflamed Adipose Tissue

Obesity is associated with an accumulation of macrophages in adipose tissue. This inflammation of adipose tissue is a key event in the pathogenesis of several obesity-related disorders, particularly insulin resistance. Here, we summarized existing model systems that mimic the situation of inflamed a...

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Autors principals: Keuper, Michaela, Dzyakanchuk, Anna, Amrein, Kurt E., Wabitsch, Martin, Fischer-Posovszky, Pamela
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355855/
https://ncbi.nlm.nih.gov/pubmed/22645513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2011.00089
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