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Antiproliferative Effects of the Natural Oxadiazine Nocuolin A Are Associated With Impairment of Mitochondrial Oxidative Phosphorylation

Natural products are interesting sources for drug discovery. The natural product oxadiazine Nocuolin A (NocA) was previously isolated from the cyanobacterial strain Nodularia sp. LEGE 06071 and here we examined its cytotoxic effects against different strains of the colon cancer cell line HCT116 and...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Sousa, Maria Lígia, Preto, Marco, Vasconcelos, Vítor, Linder, Stig, Urbatzka, Ralph
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456697/
https://ncbi.nlm.nih.gov/pubmed/31001482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00224
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