Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways

Lymphatic vessels play an important role in health and in disease. In this study, we evaluated the effects of GSK3-β inhibition on lung lymphatic endothelial cells in vitro. Pharmacological inhibition and silencing of GSK3-β resulted in increased lymphangiogenesis of lung lymphatic endothelial cells...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Stump, Benjamin, Shrestha, Shikshya, Lamattina, Anthony M., Louis, Pierce H., Cho, Woohyun, Perrella, Mark A., Ai, Xingbin, Rosas, Ivan O., Wagner, Florence F., Priolo, Carmen, Astin, Jonathan, El-Chemaly, Souheil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456176/
https://ncbi.nlm.nih.gov/pubmed/30964887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213831
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