Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways

Lymphatic vessels play an important role in health and in disease. In this study, we evaluated the effects of GSK3-β inhibition on lung lymphatic endothelial cells in vitro. Pharmacological inhibition and silencing of GSK3-β resulted in increased lymphangiogenesis of lung lymphatic endothelial cells...

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Vydáno v:PLoS One
Hlavní autoři: Stump, Benjamin, Shrestha, Shikshya, Lamattina, Anthony M., Louis, Pierce H., Cho, Woohyun, Perrella, Mark A., Ai, Xingbin, Rosas, Ivan O., Wagner, Florence F., Priolo, Carmen, Astin, Jonathan, El-Chemaly, Souheil
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456176/
https://ncbi.nlm.nih.gov/pubmed/30964887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213831
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