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Immunization with whole cell but not acellular pertussis vaccines primes CD4 T(RM) cells that sustain protective immunity against nasal colonization with Bordetella pertussis

Protective immunity wanes rapidly after immunization of children with acellular pertussis (aP) vaccines and these vaccines do not prevent nasal colonization or transmission of Bordetella pertussis in baboons. In this study, we examined the role of tissue-resident memory T (T(RM)) cells in persistent...

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書誌詳細
出版年:Emerg Microbes Infect
主要な著者: Wilk, Mieszko M., Borkner, Lisa, Misiak, Alicja, Curham, Lucy, Allen, Aideen C., Mills, Kingston H. G.
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455184/
https://ncbi.nlm.nih.gov/pubmed/30866771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2018.1564630
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