Immunization with whole cell but not acellular pertussis vaccines primes CD4 T(RM) cells that sustain protective immunity against nasal colonization with Bordetella pertussis

Protective immunity wanes rapidly after immunization of children with acellular pertussis (aP) vaccines and these vaccines do not prevent nasal colonization or transmission of Bordetella pertussis in baboons. In this study, we examined the role of tissue-resident memory T (T(RM)) cells in persistent...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Wilk, Mieszko M., Borkner, Lisa, Misiak, Alicja, Curham, Lucy, Allen, Aideen C., Mills, Kingston H. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455184/
https://ncbi.nlm.nih.gov/pubmed/30866771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2018.1564630
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