Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

Whooping cough caused by Bordetella pertussis is a re-emerging infectious disease despite the introduction of safer acellular pertussis vaccines (Pa). One explanation for this is that Pa are less protective than the more reactogenic whole cell pertussis vaccines (Pw) that they replaced. Although Pa...

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Détails bibliographiques
Auteurs principaux: Ross, Pádraig J., Sutton, Caroline E., Higgins, Sarah, Allen, Aideen C., Walsh, Kevin, Misiak, Alicja, Lavelle, Ed C., McLoughlin, Rachel M., Mills, Kingston H. G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617212/
https://ncbi.nlm.nih.gov/pubmed/23592988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003264
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