INFLUENCE OF DNA-MICROBUBBLE COUPLING ON CONTRAST ULTRASOUND-MEDIATED GENE TRANSFECTION IN MUSCLE AND LIVER

BACKGROUND. Contrast ultrasound-mediated gene delivery (CUMGD) is a promising approach for enhancing gene therapy that relies on microbubble cavitation to augment cDNA transfection. Our aims were to determine optimal conditions for charge-coupling cDNA to microbubbles, and to evaluate the advantages...

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Veröffentlicht in:J Am Soc Echocardiogr
Hauptverfasser: Xie, Aris, Wu, Melinda D., Cigarroa, Gabriella, Belcik, J. Todd, Ammi, Azzdine, Moccetti, Federico, Lindner, Jonathan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454880/
https://ncbi.nlm.nih.gov/pubmed/27267307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.echo.2016.04.011
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