Nalaganje...
Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington’s pathology in zQ175 mice
Huntington’s disease (HD) is a neurodegenerative disorder caused by a genetic abnormality in the huntingtin gene that leads to a polyglutamine repeat expansion of the huntingtin protein. The cleaved polyglutamine expansion of mutant huntingtin (mHTT) protein can form aggregates strongly correlated w...
Shranjeno v:
| izdano v: | Mol Brain |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6454676/ https://ncbi.nlm.nih.gov/pubmed/30961637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-019-0456-1 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|