Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway

BACKGROUND: Long noncoding RNAs (lncRNAs), defined as the transcripts longer than 200 nt without protein-coding capacity, have been found to be aberrantly expressed in diverse human diseases including cancer. A reciprocal translocation between chromosome 9 and 22 generates the chimeric Bcr-Abl oncog...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Wang, Xuefei, Yang, Jianling, Guo, Guijie, Feng, Riyue, Chen, Ke, Liao, Yuan, Zhang, Lianfeng, Sun, Liping, Huang, Shile, Chen, Ji-Long
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454664/
https://ncbi.nlm.nih.gov/pubmed/30961617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-019-1013-3
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