CGmapTools improves the precision of heterozygous SNV calls and supports allele-specific methylation detection and visualization in bisulfite-sequencing data

MOTIVATION: DNA methylation is important for gene silencing and imprinting in both plants and animals. Recent advances in bisulfite sequencing allow detection of single nucleotide variations (SNVs) achieving high sensitivity, but accurately identifying heterozygous SNVs from partially C-to-T convert...

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformatics
Hauptverfasser: Guo, Weilong, Zhu, Ping, Pellegrini, Matteo, Zhang, Michael Q, Wang, Xiangfeng, Ni, Zhongfu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Original Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454434/
https://ncbi.nlm.nih.gov/pubmed/28968643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx595
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