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CGmapTools improves the precision of heterozygous SNV calls and supports allele-specific methylation detection and visualization in bisulfite-sequencing data

MOTIVATION: DNA methylation is important for gene silencing and imprinting in both plants and animals. Recent advances in bisulfite sequencing allow detection of single nucleotide variations (SNVs) achieving high sensitivity, but accurately identifying heterozygous SNVs from partially C-to-T convert...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Guo, Weilong, Zhu, Ping, Pellegrini, Matteo, Zhang, Michael Q, Wang, Xiangfeng, Ni, Zhongfu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454434/
https://ncbi.nlm.nih.gov/pubmed/28968643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx595
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