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CGmapTools improves the precision of heterozygous SNV calls and supports allele-specific methylation detection and visualization in bisulfite-sequencing data

MOTIVATION: DNA methylation is important for gene silencing and imprinting in both plants and animals. Recent advances in bisulfite sequencing allow detection of single nucleotide variations (SNVs) achieving high sensitivity, but accurately identifying heterozygous SNVs from partially C-to-T convert...

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Bibliografische gegevens
Gepubliceerd in:Bioinformatics
Hoofdauteurs: Guo, Weilong, Zhu, Ping, Pellegrini, Matteo, Zhang, Michael Q, Wang, Xiangfeng, Ni, Zhongfu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454434/
https://ncbi.nlm.nih.gov/pubmed/28968643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx595
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