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Detecting hidden batch factors through data-adaptive adjustment for biological effects

MOTIVATION: Batch effects are one of the major source of technical variations that affect the measurements in high-throughput studies such as RNA sequencing. It has been well established that batch effects can be caused by different experimental platforms, laboratory conditions, different sources of...

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Bibliographische Detailangaben
Veröffentlicht in:Bioinformatics
Hauptverfasser: Yi, Haidong, Raman, Ayush T, Zhang, Han, Allen, Genevera I, Liu, Zhandong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454417/
https://ncbi.nlm.nih.gov/pubmed/29617963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx635
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