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Covariance Adjustment for Batch Effect in Gene Expression Data

Batch bias has been found in many microarray gene expression studies that involve multiple batches of samples. A serious batch effect can alter not only the distribution of individual genes but also the inter-gene relationships. Even though some efforts have been made to remove such bias, however, t...

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Detalhes bibliográficos
Main Authors: Lee, Jung Ae, Dobbin, Kevin K., Ahn, Jeongyoun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065794/
https://ncbi.nlm.nih.gov/pubmed/24687561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6157
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