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Removing Batch Effects in Analysis of Expression Microarray Data: An Evaluation of Six Batch Adjustment Methods

The expression microarray is a frequently used approach to study gene expression on a genome-wide scale. However, the data produced by the thousands of microarray studies published annually are confounded by “batch effects,” the systematic error introduced when samples are processed in multiple batc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Chao, Grennan, Kay, Badner, Judith, Zhang, Dandan, Gershon, Elliot, Jin, Li, Liu, Chunyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046121/
https://ncbi.nlm.nih.gov/pubmed/21386892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017238
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