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Adjusting for Batch Effects in DNA Methylation Microarray Data, a Lesson Learned

It is well-known, but frequently overlooked, that low- and high-throughput molecular data may contain batch effects, i.e., systematic technical variation. Confounding of experimental batches with the variable(s) of interest is especially concerning, as a batch effect may then be interpreted as a bio...

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Vydáno v:Front Genet
Hlavní autoři: Price, E. M., Robinson, Wendy P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864890/
https://ncbi.nlm.nih.gov/pubmed/29616078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00083
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