Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus

Coagulation factor XII (FXII) plays a crucial role in thrombosis. Moreover, deficiencies in FXII are not associated with excessive bleeding, and its depletion exhibits satisfactory protective effect on thrombus formation. Several strategies targeting FXII have been applied to inhibit thrombosis form...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Li, Fanfan, Yang, Xiao, Liu, Jie, Shu, Kuangyi, Shen, Chenfang, Chen, Tao, Yang, Wei, Li, Shanshan, Wang, Xiaoou, Jiang, Minghua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454094/
https://ncbi.nlm.nih.gov/pubmed/30959404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.02.026
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