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Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus

Coagulation factor XII (FXII) plays a crucial role in thrombosis. Moreover, deficiencies in FXII are not associated with excessive bleeding, and its depletion exhibits satisfactory protective effect on thrombus formation. Several strategies targeting FXII have been applied to inhibit thrombosis form...

詳細記述

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書誌詳細
出版年:Mol Ther Nucleic Acids
主要な著者: Li, Fanfan, Yang, Xiao, Liu, Jie, Shu, Kuangyi, Shen, Chenfang, Chen, Tao, Yang, Wei, Li, Shanshan, Wang, Xiaoou, Jiang, Minghua
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454094/
https://ncbi.nlm.nih.gov/pubmed/30959404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.02.026
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