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Antithrombotic Effect of shRNA Target F12 Mediated by Adeno-Associated Virus
Coagulation factor XII (FXII) plays a crucial role in thrombosis. Moreover, deficiencies in FXII are not associated with excessive bleeding, and its depletion exhibits satisfactory protective effect on thrombus formation. Several strategies targeting FXII have been applied to inhibit thrombosis form...
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| Publié dans: | Mol Ther Nucleic Acids |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Gene & Cell Therapy
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6454094/ https://ncbi.nlm.nih.gov/pubmed/30959404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.02.026 |
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