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The fitness cost and benefit of phase‐separated protein deposits

Phase separation of soluble proteins into insoluble deposits is associated with numerous diseases. However, protein deposits can also function as membrane‐less compartments for many cellular processes. What are the fitness costs and benefits of forming such deposits in different conditions? Using a...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Principais autores: Sanchez de Groot, Natalia, Torrent Burgas, Marc, Ravarani, Charles NJ, Trusina, Ala, Ventura, Salvador, Babu, M Madan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452874/
https://ncbi.nlm.nih.gov/pubmed/30962358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20178075
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