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Centrality in the host–pathogen interactome is associated with pathogen fitness during infection

To perform their functions proteins must interact with each other, but how these interactions influence bacterial infection remains elusive. Here we demonstrate that connectivity in the host–pathogen interactome is directly related to pathogen fitness during infection. Using Y. pestis as a model org...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Crua Asensio, Núria, Muñoz Giner, Elisabet, de Groot, Natalia Sánchez, Torrent Burgas, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5241799/
https://ncbi.nlm.nih.gov/pubmed/28090086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14092
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