Age-related inflammation triggers skeletal stem/progenitor cell dysfunction

Aging is associated with impaired tissue regeneration. Stem cell number and function have been identified as potential culprits. We first demonstrate a direct correlation between stem cell number and time to bone fracture union in a human patient cohort. We then devised an animal model recapitulatin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Josephson, Anne Marie, Bradaschia-Correa, Vivian, Lee, Sooyeon, Leclerc, Kevin, Patel, Karan S., Muinos Lopez, Emma, Litwa, Hannah P., Neibart, Shane S., Kadiyala, Manasa, Wong, Madeleine Z., Mizrahi, Matthew M., Yim, Nury L., Ramme, Austin J., Egol, Kenneth A., Leucht, Philipp
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452701/
https://ncbi.nlm.nih.gov/pubmed/30894483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810692116
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge