FLUOXETINE INHIBITS OSTEOBLAST DIFFERENTIATION & MINERALIZATION IN FRACTURE HEALING: The Selective Serotonin Reuptake Inhibitor Fluoxetine Directly Inhibits Osteoblast Differentiation and Mineralization During Fracture Healing in Mice

Chronic use of selective serotonin reuptake inhibitors (SSRIs) for the treatment of depression has been linked to osteoporosis. In this study, we investigated the effect of chronic SSRI use on fracture healing in two murine models of bone regeneration. First, we performed a comprehensive analysis of...

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Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Bradaschia-Correa, Vivian, Josephson, Anne M, Mehta, Devan, Mizrahi, Matthew, Neibart, Shane S, Liu, Chao, Kennedy, Oran, Castillo, Alesha B, Egol, Kenneth A, Leucht, Philipp
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395314/
https://ncbi.nlm.nih.gov/pubmed/27869327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3045
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