Quality Control of Therapeutic Peptides by (1)H NMR HiFSA Sequencing

Ensuring identity, purity, and reproducibility are equally essential during synthetic chemistry, drug discovery, and for pharmaceutical product safety. Many peptidic APIs are large molecules that require considerable effort for integrity assurance. This study builds on quantum mechanical (1)H iterat...

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Gepubliceerd in:J Org Chem
Hoofdauteurs: Choules, Mary P., Bisson, Jonathan, Gao, Wei, Lankin, David C., McAlpine, James B., Niemitz, Matthias, Jaki, Birgit U., Franzblau, Scott G., Pauli, Guido F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452441/
https://ncbi.nlm.nih.gov/pubmed/30793905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b02704
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