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Intrathecal cyclodextrin in the treatment of Niemann-Pick disease type C

CASE: A child with Niemann-Pick disease type C was started on miglustat therapy at the age of 2 years. Intrathecal administration of hydroxypropyl-β-cyclodextrin was added 5 months later. The initial dose of 175 mg was gradually increased over the first 6 months to reach 325 mg. The drug was adminis...

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Publicat a:Eur J Hosp Pharm
Autors principals: Roch Santed, Maria, Cabañas Poy, Maria Josep, Del Toro Riera, Mireia, Cañete Ramírez, Carme, Fernández Polo, Aurora, Clemente Bautista, Susana
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451626/
https://ncbi.nlm.nih.gov/pubmed/31156935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ejhpharm-2016-001067
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