Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP–DNA dissociation

The TATA-box Binding Protein (TBP) plays a central role in regulating gene expression and is the first step in the process of pre-initiation complex (PIC) formation on promoter DNA. The lifetime of TBP at the promoter site is controlled by several cofactors including the Modifier of transcription 1...

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Udgivet i:Nucleic Acids Res
Main Authors: Heiss, Gregor, Ploetz, Evelyn, Voith von Voithenberg, Lena, Viswanathan, Ramya, Glaser, Samson, Schluesche, Peter, Madhira, Sushi, Meisterernst, Michael, Auble, David T, Lamb, Don C
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451094/
https://ncbi.nlm.nih.gov/pubmed/30649478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1322
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