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Development of an ex vivo respiratory pediatric model of bronchopulmonary dysplasia for aerosol deposition studies

Ethical restrictions are limitations of in vivo inhalation studies, on humans and animal models. Thus, in vitro or ex vivo anatomical models offer an interesting alternative if limitations are clearly identified and if extrapolation to human is made with caution. This work aimed to develop an ex viv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Montigaud, Yoann, Périnel, Sophie, Dubus, Jean-Christophe, Leclerc, Lara, Suau, Marie, Goy, Clémence, Clotagatide, Anthony, Prévôt, Nathalie, Pourchez, Jérémie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450907/
https://ncbi.nlm.nih.gov/pubmed/30952897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42103-2
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