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Simvastatin Promotes Restoration of Chondrocyte Morphology and Phenotype

In this study we examined whether the action of simvastatin affects re-differentiation of passaged chondrocytes and if so, whether this was mediated via changes in cholesterol or cholesterol intermediates. Bovine articular chondrocytes, of varying passage number, human knee chondrocytes and rat chon...

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Detalhes bibliográficos
Publicado no:Arch Biochem Biophys
Main Authors: Terabe, Kenya, Takahashi, Nobunori, Cobb, Michelle, Askew, Emily B., Knudson, Cheryl B., Knudson, Warren
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450767/
https://ncbi.nlm.nih.gov/pubmed/30776329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2019.01.038
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