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The Notch signaling pathway controls CD8(+) T cell differentiation independently of the classical effector HES1
During CD8(+) T cell response, Notch signaling controls short-lived-effector-cell (SLEC) generation, but the exact mechanisms by which it does so remains unclear. The Notch signaling pathway can act as a key regulator of Akt signaling via direct transcriptional induction of Hes1, which will then rep...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450647/ https://ncbi.nlm.nih.gov/pubmed/30951556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215012 |
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