The Catalytic Activity of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 3 Is Required To Sustain CD4(+) CD8(+) Thymocyte Survival

Extracellular signal-regulated kinase 3 (ERK3) is an atypical member of the mitogen-activated protein kinase (MAPK) family whose function is largely unknown. Given the central role of MAPKs in T cell development, we hypothesized that ERK3 may regulate thymocyte development. Here we have shown that E...

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Main Authors: Marquis, Miriam, Daudelin, Jean-François, Boulet, Salix, Sirois, Julien, Crain, Karinn, Mathien, Simon, Turgeon, Benjamin, Rousseau, Justine, Meloche, Sylvain, Labrecque, Nathalie
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135614/
https://ncbi.nlm.nih.gov/pubmed/25002529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01701-13
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