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The Notch signaling pathway controls CD8(+) T cell differentiation independently of the classical effector HES1
During CD8(+) T cell response, Notch signaling controls short-lived-effector-cell (SLEC) generation, but the exact mechanisms by which it does so remains unclear. The Notch signaling pathway can act as a key regulator of Akt signaling via direct transcriptional induction of Hes1, which will then rep...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450647/ https://ncbi.nlm.nih.gov/pubmed/30951556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215012 |
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