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In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers
A combination of biochemical, biophysical and biological techniques was used to study calf thymus DNA interaction with newly synthesized 7-MEOTA-tacrine thiourea 12–17 and urea heterodimers 18–22, and to measure interference with type I and II topoisomerases. Their biological profile was also inspec...
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| Publicat a: | J Enzyme Inhib Med Chem |
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| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6450562/ https://ncbi.nlm.nih.gov/pubmed/30938202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1593159 |
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