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Doxorubicin-loaded red blood cells reduced cardiac toxicity and preserved anticancer activity

Doxorubicin (DOX) is one of the most widely used anticancer agents. DOX is known for inducing cardiotoxicity, resulting in the long-term development of heart failure. Intravascular delivery of DOX may benefit from the carriage by red blood cells (RBCs), as they can limit the systemic toxicity while...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Lucas, Alfredo, Lam, Dawn, Cabrales, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450495/
https://ncbi.nlm.nih.gov/pubmed/30929538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1591544
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