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Surface functionalization of doxorubicin-loaded liposomes with octa-arginine for enhanced anticancer activity
Doxorubicin-loaded PEGylated liposomes (commercially available as DOXIL(®) or Lipodox(®)) were surface functionalized with a cell-penetrating peptide, octa-arginine (R8). For this purpose, R8-peptide was conjugated to the polyethylene glycol–dioleoyl phosphatidylethanolamine (PEG–DOPE) amphiphilic c...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157068/ https://ncbi.nlm.nih.gov/pubmed/23333899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2012.12.021 |
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