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Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting

A novel mitochondrial-targeted liposomal drug-delivery system was prepared by modification of the liposomal surface with a newly synthesized polymer, rhodamine-123 (Rh123)-PEG-DOPE inserted into the liposomal lipid bilayer. This novel polymer was synthesized by conjugating the mitochondriotropic dye...

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Detalhes bibliográficos
Main Authors: Biswas, Swati, Dodwadkar, Namita S., Sawant, Rupa R., Koshkaryev, Alexander, Torchilin, Vladimir P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492939/
https://ncbi.nlm.nih.gov/pubmed/21348804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2010.536983
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