Cross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization

Adjuvanted whole inactivated virus (WIV) influenza vaccines show promise as broadly protective influenza vaccine candidates. Using WIV as basis we assessed the relative efficacy of different adjuvants by carrying out a head-to-head comparison of the liposome-based adjuvants CAF01 and CAF09 and the p...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bhide, Yoshita, Dong, Wei, Gribonika, Inta, Voshart, Daniëlle, Meijerhof, Tjarko, de Vries-Idema, Jacqueline, Norley, Stephen, Guilfoyle, Kate, Skeldon, Sarah, Engelhardt, Othmar G., Boon, Louis, Christensen, Dennis, Lycke, Nils, Huckriede, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450434/
https://ncbi.nlm.nih.gov/pubmed/30984200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00646
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