Induction of Heterosubtypic Cross-Protection against Influenza by a Whole Inactivated Virus Vaccine: The Role of Viral Membrane Fusion Activity

BACKGROUND: The inability of seasonal influenza vaccines to effectively protect against infection with antigenically drifted viruses or newly emerging pandemic viruses underlines the need for development of cross-reactive influenza vaccines that induce immunity against a variety of virus subtypes. T...

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Detalhes bibliográficos
Main Authors: Budimir, Natalija, Huckriede, Anke, Meijerhof, Tjarko, Boon, Louis, Gostick, Emma, Price, David A., Wilschut, Jan, de Haan, Aalzen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267744/
https://ncbi.nlm.nih.gov/pubmed/22303469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030898
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