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Evaluation of an Intranasal Virosomal Vaccine against Respiratory Syncytial Virus in Mice: Effect of TLR2 and NOD2 Ligands on Induction of Systemic and Mucosal Immune Responses

INTRODUCTION: RSV infection remains a serious threat to newborns and the elderly. Currently, there is no vaccine available to prevent RSV infection. A mucosal RSV vaccine would be attractive as it could induce mucosal as well as systemic antibodies, capable of protecting both the upper and lower res...

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Autors principals: Shafique, Muhammad, Meijerhof, Tjarko, Wilschut, Jan, de Haan, Aalzen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620164/
https://ncbi.nlm.nih.gov/pubmed/23593453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061287
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