Critical Role of TLR7 Signaling in the Priming of Cross-Protective Cytotoxic T Lymphocyte Responses by a Whole Inactivated Influenza Virus Vaccine

Current influenza vaccines fail to induce protection against antigenically distinct virus strains. Accordingly, there is a need for the development of cross-protective vaccines. Previously, we and others have shown that vaccination with whole inactivated virus (WIV) induces cross-protective cellular...

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Hauptverfasser: Budimir, Natalija, de Haan, Aalzen, Meijerhof, Tjarko, Waijer, Simke, Boon, Louis, Gostick, Emma, Price, David A., Wilschut, Jan, Huckriede, Anke
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642048/
https://ncbi.nlm.nih.gov/pubmed/23658804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063163
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