Cross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization

Adjuvanted whole inactivated virus (WIV) influenza vaccines show promise as broadly protective influenza vaccine candidates. Using WIV as basis we assessed the relative efficacy of different adjuvants by carrying out a head-to-head comparison of the liposome-based adjuvants CAF01 and CAF09 and the p...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Bhide, Yoshita, Dong, Wei, Gribonika, Inta, Voshart, Daniëlle, Meijerhof, Tjarko, de Vries-Idema, Jacqueline, Norley, Stephen, Guilfoyle, Kate, Skeldon, Sarah, Engelhardt, Othmar G., Boon, Louis, Christensen, Dennis, Lycke, Nils, Huckriede, Anke
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450434/
https://ncbi.nlm.nih.gov/pubmed/30984200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00646
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